In addition to these recommendations, check all trailer tires (including spares) for signs of dry rot, correct air pressure, faulty air valves, uneven tire wear, overall tire wear and damage. Get a high-quality air pressure gauge, and learn how to use it, so you can inspect tire pressure before each trip. (Trailer tires should be replaced if they’re worn or damaged. Otherwise, replacement every three to five years is the rule of thumb.)
It is also important to service the wheel bearings every 12,000 miles, or annually, regardless of mileage, due to moisture build-up. Keep a spare set of wheel bearings in your trailer in case of premature failure. Be sure to inspect trailer wiring and lighting; inspect door latches and grease the doors; inspect the floor (be sure to remove any rubber mats so the entire floor can be examined); and inspect and lubricate mechanical moving parts, such as the hitch and suspension parts. If the trailer has been sitting for a while, check for wasp nests, spider webs and any other creatures.